Our History
From 2011 to Today, This Is
What Staying Local Looks
Like
Hannibal Pharmacy opened its doors in August 2011, bringing a true hometown drugstore back to Hannibal after twenty-five years. Jack and Erin Hess built the pharmacy on a simple pledge: we listen, we care, and we deliver. Every refill since has been counted, checked, and handed over by someone who knows you by name. Through blizzards, blackouts, and a global pandemic the lights stayed on, prescriptions reached front porches, and the phone never rolled to voicemail. Family ownership remains, the commitment to community grows, and neighbors across Hannibal, Fulton, and all of Oswego County rely on us more than ever.
Our Vision
To remain Hannibal’s most trusted community pharmacy and healthcare comfort zone.
Our Mission
To deliver fast, convenient, and personalized care for every neighbor, every time.


The Hannibal Pharmacy Difference
Why We're Trusted
The Secret Behind Our Loyal Customers
Trust grows from relationships, not transactions. Hannibal Pharmacy’s neighbors keep coming back because we know their names, their stories, and their needs. From friendly advice over the counter to timely delivery at the doorstep, every interaction reflects our commitment to personal care that never wavers.
Deep Community Commitment
Pharmacists with Real Experience
Care Designed for Your Life
OUR COMMITMENT
Care That Follows You Home
Since 2011 Hannibal Pharmacy has stood for personal, fast, and convenient care. Friendly experts answer every call, prescriptions arrive on schedule, and clear answers replace confusion. We listen, we care, and we deliver, every neighbor, every time.
Easy Transfers
Our team calls your old pharmacy and doctor, moves every prescription, and lets you know when it’s ready. No paperwork on your end.
Fast Refills
Most orders are filled in ten minutes, synced for one pickup, or delivered the same day within Hannibal and Fulton.

Our Team
Meet the Neighbors Who Keep You Healthy
For more than a decade, our award-winning pharmacists and caring support staff blend clinical know-how with genuine compassion. Each visit comes with clear guidance, extra time for questions, and the steady reassurance that a trusted neighbor is handling your care.
100+
Years of Combined Experience
Award-Winning Pharmacists
Neighbors Who Know You by Name
Community-Focused Service
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Friendly Experts

Need more help?
Still have questions? Call 315-564-6464 and speak with our friendly team. contact us for personalized help
Frequently Asked Questions
Got a question about prescriptions, vaccines, or delivery? Check the answers below. If you do not see what you need, just give us a call and we will be happy to help.
Yes. Free delivery is offered in Hannibal, Fulton, and nearby parts of Oswego County.
Tell us the name of your current pharmacy and the medications you need. We contact them and your doctor, then let you know when everything is ready.
Walk in for flu, shingles, pneumonia, and COVID boosters. Other vaccines can be scheduled with a quick phone call.
Yes. Download the free RxLocal app from the App Store or Google Play to request refills, set reminders, and message our pharmacists 24/7.
Hannibal Pharmacy App
Your Prescriptions, One Tap Away
Powered by the secure RxLocal platform, our free app lets you request refills 24/7, set medication reminders, and message our pharmacists with a single tap. Stay in control of every prescription whether you are in Hannibal, visiting Fulton, or traveling across the country. Download today and experience our promise: we listen, we care, and we deliver.
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Testimonials
Our Customers Say It Best
Neighbors across Hannibal and Fulton trust us with their health every day. Their words capture the service, care, and hometown spirit we bring to every prescription.

Request a CallBack
Need help with a prescription, delivery, or insurance question? Share your details and one of our friendly team members will call you back shortly. We listen, we care, and we deliver, even when it comes to returning your call.